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Literature summary for 1.17.3.2 extracted from

  • Hayden, T.J.; Ryan, J.P.; Duke, E.J.
    Comparative aspects of xanthine-oxygen oxidoreductase systems (1973), Biochem. Soc. Trans., 1, 247-250.
No PubMed abstract available

Inhibitors

Inhibitors Comment Organism Structure
Azaguanine
-
Locusta sp.

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
additional information
-
Drosophila melanogaster
additional information
-
additional information
-
Mus musculus
additional information
-
additional information
-
Locusta sp.
0.00143
-
2-Amino-4-hydroxypteridine + methylene blue Locusta sp.
0.0067
-
2-Amino-4-hydroxypteridine + methylene blue Drosophila melanogaster
0.024
-
xanthine kidney enzyme Gallus gallus
0.025
-
xanthine
-
Mus musculus
0.13
-
xanthine
-
Locusta sp.
0.26
-
xanthine liver enzyme Gallus gallus

Metals/Ions

Metals/Ions Comment Organism Structure
Iron iron-molybdenum protein Gallus gallus
Iron iron-molybdenum protein Drosophila melanogaster
Iron iron-molybdenum protein Mus musculus
Iron iron-molybdenum protein Locusta sp.
Molybdenum an iron-molybdenum protein Gallus gallus
Molybdenum an iron-molybdenum protein Drosophila melanogaster
Molybdenum an iron-molybdenum protein Mus musculus
Molybdenum an iron-molybdenum protein Locusta sp.

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster
-
-
-
Gallus gallus
-
-
-
Locusta sp.
-
-
-
Mus musculus
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
additional information
-
Gallus gallus
additional information
-
Drosophila melanogaster
additional information
-
Mus musculus
additional information
-
Locusta sp.
proteolytic modification
-
Gallus gallus
proteolytic modification
-
Drosophila melanogaster
proteolytic modification
-
Mus musculus
proteolytic modification
-
Locusta sp.

Source Tissue

Source Tissue Comment Organism Textmining
duodenum
-
Mus musculus
-
duodenum
-
Locusta sp.
-
kidney
-
Mus musculus
-
kidney
-
Locusta sp.
-
liver
-
Gallus gallus
-
liver
-
Mus musculus
-
liver
-
Locusta sp.
-
lung
-
Mus musculus
-
lung
-
Locusta sp.
-
pancreas
-
Mus musculus
-
pancreas
-
Locusta sp.
-
spleen
-
Mus musculus
-
spleen
-
Locusta sp.
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-amino-4-hydroxypteridine + H2O + O2
-
Drosophila melanogaster ?
-
r
2-amino-4-hydroxypteridine + H2O + O2
-
Locusta sp. ?
-
r
hypoxanthine + 2 H2O + 2 O2
-
Gallus gallus urate + 2 H2O2
-
?
hypoxanthine + 2 H2O + 2 O2
-
Drosophila melanogaster urate + 2 H2O2
-
?
hypoxanthine + 2 H2O + 2 O2
-
Mus musculus urate + 2 H2O2
-
?
hypoxanthine + 2 H2O + 2 O2
-
Locusta sp. urate + 2 H2O2
-
?
xanthine + H2O + O2 electron acceptor O2 Gallus gallus uric acid + H2O2
-
?
xanthine + H2O + O2 electron acceptor O2 Drosophila melanogaster uric acid + H2O2
-
?
xanthine + H2O + O2 electron acceptor O2 Mus musculus uric acid + H2O2
-
?
xanthine + H2O + O2 electron acceptor O2 Locusta sp. uric acid + H2O2
-
?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
-
Locusta sp.

Cofactor

Cofactor Comment Organism Structure
FAD flavoprotein Gallus gallus
FAD flavoprotein Drosophila melanogaster
FAD flavoprotein Mus musculus
FAD flavoprotein Locusta sp.