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Literature summary for 1.17.1.4 extracted from

  • Settle, T.; Carro, M.D.; Falkenstein, E.; Radke, W.; Klandorf, H.
    The effects of allopurinol, uric acid, and inosine administration on xanthine oxidoreductase activity and uric acid concentrations in broilers (2012), Poult. Sci., 91, 2895-2903.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
allopurinol XOR activity in liver reduced by allopurinol treatment, no effect in kidney. Birds fed with inosine and allopurinol show lower total XOR activity in liver but no effect in kidney Gallus gallus

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
Gallus gallus
-
liver XOR activity reduced by allopurinol treatment. Birds fed with inosine and allopurinol show lower total XOR activity in liver but no effect in kidney Gallus gallus
-
plasma
-
Gallus gallus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
xanthine + NAD+ + H2O
-
Gallus gallus urate + NADH
-
?

Synonyms

Synonyms Comment Organism
xanthine oxidoreductase
-
Gallus gallus
XOR
-
Gallus gallus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
41
-
assay at Gallus gallus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.8
-
assay at Gallus gallus