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Literature summary for 1.17.1.4 extracted from

  • Godber, B.L.; Schwarz, G.; Mendel, R.R.; Lowe, D.J.; Bray, R.C.; Eisenthal, R.; Harrison, R.
    Molecular characterization of human xanthine oxidoreductase: the enzyme is grossly deficient in molybdenum and substantially deficient in iron-sulphur centres (2005), Biochem. J., 388, 501-508.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.17.1.4

Metals/Ions

Metals/Ions Comment Organism Structure
Iron enzyme is about 30% deficient in iron-sulfur centers on basis of UV/vis and CD spectra Homo sapiens
Molybdenum 0.04 atoms per subunit Homo sapiens
Molybdenum 0.61 atoms per subunit Bos taurus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
148000
-
 x * 148000, MALDI-TOF Homo sapiens
148300
-
 x * 148300, MALDI-TOF Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Bos taurus xanthine oxidoreductase plays a physiological role in milk equal in importance to its catalytic function as an enzyme ?
-
 ?
additional information Homo sapiens xanthine oxidoreductase plays a physiological role in milk equal in importance to its catalytic function as an enzyme ?
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Homo sapiens P47989
-
-

Source Tissue

Source Tissue Comment Organism Textmining
milk
-
 Bos taurus
-
milk
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information xanthine oxidoreductase plays a physiological role in milk equal in importance to its catalytic function as an enzyme Bos taurus ?
-
 ?
additional information xanthine oxidoreductase plays a physiological role in milk equal in importance to its catalytic function as an enzyme Homo sapiens ?
-
 ?

Subunits

Subunits Comment Organism
? x * 148000, MALDI-TOF Homo sapiens
? x * 148300, MALDI-TOF Bos taurus

Cofactor

Cofactor Comment Organism Structure
FAD 1 mol per mol of subunit Bos taurus
FAD 1 mol per mol of subunit Homo sapiens
molybdopterin 0.09 molecules per subunit Homo sapiens
molybdopterin 0.62 molecules per subunit Bos taurus