Literature summary for 1.16.3.1 extracted from

Yokoyama, H.; Tsuruta, O.; Akao, N.; Fujii, S.
Crystal structure of Helicobacter pylori neutrophil-activating protein with a di-nuclear ferroxidase center in a zinc or cadmium-bound form (2012), Biochem. Biophys. Res. Commun., 422, 745-750.

Crystallization (Commentary)

Crystallization (Comment)	Organism
crystal structures of Zn2+- and Cd2+-bound forms of HP-NAP, and Cd2+-bound and apo forms of HP-NAP are determined: The coordination patterns of Zn2+ and Cd2+ are different but both metal ions can bind to the ferroxidase center (FOC), indicating that HP-NAP can store zinc and cadmium ions in addition to iron ions. Another zinc ion is found inside of the negatively-charged 3fold-related pore, as an iron ion in the iron-containing form, and therefore the pore is suitable for metal ions to pass through	Helicobacter pylori

Crystallization (Comment)

Organism

crystal structures of Zn2+- and Cd2+-bound forms of HP-NAP, and Cd2+-bound and apo forms of HP-NAP are determined: The coordination patterns of Zn2+ and Cd2+ are different but both metal ions can bind to the ferroxidase center (FOC), indicating that HP-NAP can store zinc and cadmium ions in addition to iron ions. Another zinc ion is found inside of the negatively-charged 3fold-related pore, as an iron ion in the iron-containing form, and therefore the pore is suitable for metal ions to pass through

Helicobacter pylori

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Cd2+	crystal structures of Zn2+- and Cd2+-bound forms of HP-NAP, and Cd2+-bound and apo forms of HP-NAP are determined: The coordination patterns of Zn2+ and Cd2+ are different but both metal ions can bind to the ferroxidase center (FOC)	Helicobacter pylori
Zn2+	crystal structures of Zn2+- and Cd2+-bound forms of HP-NAP, and Cd2+-bound and apo forms of HP-NAP are determined: The coordination patterns of Zn2+ and Cd2+ are different but both metal ions can bind to the ferroxidase center (FOC)	Helicobacter pylori

Organism

Organism	UniProt	Comment	Textmining
Helicobacter pylori	G1UIZ2	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

Synonyms

Synonyms	Comment	Organism
HP-NAP	-	Helicobacter pylori
neutrophil-activating protein	-	Helicobacter pylori

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)