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Literature summary for 1.16.1.8 extracted from

  • Elmore, C.L.; Wu, X.; Leclerc, D.; Watson, E.D.; Bottiglieri, T.; Krupenko, N.I.; Krupenko, S.A.; Cross, J.C.; Rozen, R.; Gravel, R.A.; Matthews, R.G.
    Metabolic derangement of methionine and folate metabolism in mice deficient in methionine synthase reductase (2007), Mol. Genet. Metab., 91, 85-97.
    View publication on PubMedView publication on EuropePMC
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Protein Variants

Protein Variants Comment Organism
additional information construction of mouse model with a gene trap in the methionine synthase reductase gene. Mutant animals have increased plasma homocyst(e)ine, decreased plasma methionine, and increased tissue methyltetrahydrofolate levels. Mice do not show decreases in the S-adenosylmethionine/S-adenosylhomocysteine ratio in most tissues Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
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