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Literature summary for 1.16.1.1 extracted from
- The effect of 2,4,6-trinitrobenzenesulfonate on mercuric reductase, glutathione reductase and lipoamide dehydrogenase (1985), FEBS Lett., 180, 102-106.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | 0.1 mM NADP+ stimulates the 2,4,6-trinitrobenzenesulfonate-dependent NADPH oxidation more than 10fold | Pseudomonas aeruginosa | |
| NADP+ | strong stimulation of the reaction with 2,4,6-trinitrobenzenesulfonate and NADPH | Pseudomonas aeruginosa |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | no inhibition by 2,4,6-trinitrobenzenesulfonate; not inhibitory: 0.1 mM NADP+; not inhibitory: 100 microM 2,4,6-trinitrobenzenesulfonate | Pseudomonas aeruginosa | |
| NADPH | substrate inhibition of the reaction with 2,4,6-trinitrobenzenesulfonate and NADPH | Pseudomonas aeruginosa | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
| Pseudomonas aeruginosa | - |
- |
- |
| Pseudomonas aeruginosa | - |
PAO9501 | - |
| Pseudomonas aeruginosa PAO 9501 | - |
- |
- |
| Pseudomonas aeruginosa PAO9501 | - |
PAO9501 | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2,4,6-trinitrobenzenesulfonate + NADPH | - |
Pseudomonas aeruginosa | ? + NADP+ | - |
? | |
| 2,4,6-trinitrobenzenesulfonate + NADPH | - |
Pseudomonas aeruginosa PAO9501 | ? + NADP+ | - |
? | |
| 2,4,6-trinitrobenzenesulfonate + NADPH | - |
Pseudomonas aeruginosa PAO 9501 | ? + NADP+ | - |
? | |
| Hg2+ + NADPH | - |
Escherichia coli | Hg + NADP+ + H+ | - |
? | |
| Hg2+ + NADPH | - |
Pseudomonas aeruginosa | Hg + NADP+ + H+ | - |
? | |
| Hg2+ + NADPH | - |
Pseudomonas aeruginosa PAO9501 | Hg + NADP+ + H+ | - |
? | |
| Hg2+ + NADPH | - |
Pseudomonas aeruginosa PAO 9501 | Hg + NADP+ + H+ | - |
? | |
| NADPH + Hg2+ | - |
Pseudomonas aeruginosa | NADP+ + Hg | - |
? | |
| NADPH + Hg2+ | - |
Pseudomonas aeruginosa PAO9501 | NADP+ + Hg | - |
? | |
| NADPH + Hg2+ | - |
Pseudomonas aeruginosa PAO 9501 | NADP+ + Hg | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| mercuric reductase | - |
Pseudomonas aeruginosa |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| FAD | - |
Pseudomonas aeruginosa | |
| NADPH | - |
Escherichia coli | |
| NADPH | - |
Pseudomonas aeruginosa | |
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