Protein Variants | Comment | Organism |
---|---|---|
E12Q | mutation in corrdination site of iron. Detailed kinetic analysis | Archaeoglobus fulgidus |
E12V | mutation in corrdination site of iron. Detailed kinetic analysis | Archaeoglobus fulgidus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Iron | 0.8 atoms per subunit for wild-type, mutant E12V, 1.2 atoms per subunit, mutant E12Q, 0.9 atoms per subunit | Archaeoglobus fulgidus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Archaeoglobus fulgidus | - |
Fe-SOR isoform neelaredoxin | - |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
superoxide + reduced rubredoxin + 2 H+ = H2O2 + oxidized rubredoxin | the initial reaction between O2- and Archaeoglobus fulgidus neelaredoxin leads to a short-lived transient that immediately disappears to yield a solvent-bound ferric species in acid-base equilibrium. The final step corresponds to the slow binding of the glutamate sixth ligand to the oxidized iron, a process that may be bypassed during in vivo catalytic turnover of the enzyme | Archaeoglobus fulgidus |