Literature summary for 1.15.1.1 extracted from

Braesen, J.H.; Leppaenen, O.; Inkala, M.; Heikura, T.; Levin, M.; Ahrens, F.; Rutanen, J.; Pietsch, H.; Bergqvist, D.; Levonen, A.L.; Basu, S.; Zeller, T.; Kloeppel, G.; Laukkanen, M.O.; Ylae-Herttuala, S.
Extracellular superoxide dismutase accelerates endothelial recovery and inhibits in-stent restenosis in stented atherosclerotic Watanabe heritable hyperlipidemic rabbit aorta (2007), J. Am. Coll. Cardiol., 50, 2249-2253.

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Cloned(Commentary)

Cloned (Comment)	Organism
construction of replication-deficient E1-partially E3-deleted clinical good manufacturing practice-grade adenoviruses encoding rabbit EC-SOD, free from contaminants, infusion of rabbit aorta segments, overview	Oryctolagus cuniculus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
extracellular	-	Oryctolagus cuniculus	-	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
O2.- + H+	Oryctolagus cuniculus	extracellular superoxide dismutase accelerates endothelial recovery and inhibits in-stent restenosis in stented atherosclerotic Watanabe heritable hyperlipidemic rabbit aorta. Extracellular superoxide dismutase, EC-SOD, is a major component of antioxidative defense in blood vessels, and exogenously delivered EC-SOD protects against balloon-induced neointima formation and constrictive remodeling and has powerful cardioprotective properties, overview	O2 + H2O2	-	?

Organism

Organism	UniProt	Comment	Textmining
Oryctolagus cuniculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
blood	-	Oryctolagus cuniculus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
O2.- + H+	-	Oryctolagus cuniculus	O2 + H2O2	-	?
O2.- + H+	extracellular superoxide dismutase accelerates endothelial recovery and inhibits in-stent restenosis in stented atherosclerotic Watanabe heritable hyperlipidemic rabbit aorta. Extracellular superoxide dismutase, EC-SOD, is a major component of antioxidative defense in blood vessels, and exogenously delivered EC-SOD protects against balloon-induced neointima formation and constrictive remodeling and has powerful cardioprotective properties, overview	Oryctolagus cuniculus	O2 + H2O2	-	?

Synonyms

Synonyms	Comment	Organism
EC-SOD	-	Oryctolagus cuniculus
SOD	-	Oryctolagus cuniculus

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Release 2023.1 (January 2023)