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Literature summary for 1.15.1.1 extracted from

  • Raza, F.S.; Okamoto, M.; Takemori, H.; Vinson, G.P.
    Manganese superoxide dismutase activity in the rat adrenal (2005), J. Endocrinol., 184, 77-84.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
corticotrophin enzyme activity in the inner zone mitochondria of adrenal gland is enhaced by corticotrophin and by a low-sodium diet Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus MnSOD may have a specific role in the steroidogenic function of the fasciulata/reticularis of the rat adrenal, but not on that of the glomerulosa ?
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?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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isoform MnSOD
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Source Tissue

Source Tissue Comment Organism Textmining
adrenal gland enzyme mRNA is only found in the inner zones of adrenal cortex, not the glomerulosa. Enzyme activity in the inner zone mitochondria is enhaced by corticotrophin and by a low-sodium diet, but suppressed by betamethasone Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information MnSOD may have a specific role in the steroidogenic function of the fasciulata/reticularis of the rat adrenal, but not on that of the glomerulosa Rattus norvegicus ?
-
?

Subunits

Subunits Comment Organism
More immunoblot analysis shows isoforms of 25 and 75 kDa with increased expression of the 75 kDa isoform after treatment with corticotrophin Rattus norvegicus