Literature summary for 1.14.99.63 extracted from

Tao, L.; Wilczek, J.; Odom, J.M.; Cheng, Q.
Engineering a beta-carotene ketolase for astaxanthin production (2006), Metab. Eng., 8, 523-531 .

Search for more literature for 1.14.99.63

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Sphingomonas sp. DC18

Protein Variants

Protein Variants	Comment	Organism
A205V	mutation improves astaxanthin production	Sphingomonas sp. DC18
A208V	mutation improves astaxanthin production	Sphingomonas sp. DC18
A215T	mutation improves astaxanthin production	Sphingomonas sp. DC18
F213L	mutant enzyme shows high improvement for astaxanthin production and decreased activity for canthaxanthin production	Sphingomonas sp. DC18
F213L	mutation improves astaxanthin production	Sphingomonas sp. DC18
H96L	mutation improves astaxanthin production	Sphingomonas sp. DC18
R203W	mutation improves astaxanthin production	Sphingomonas sp. DC18
R203W/F213L	mutant enzyme shows high improvement for astaxanthin production and decreased activity for canthaxanthin production	Sphingomonas sp. DC18
R203W/F213L	mutation improves astaxanthin production	Sphingomonas sp. DC18

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
beta-carotene + 2 reduced acceptor + 2 O2	Sphingomonas sp. DC18	-	echinenone + 2 acceptor + 3 H2O	-	?
echinenone + 2 reduced acceptor + 2 O2	Sphingomonas sp. DC18	-	canthaxanthin + 2 acceptor + 3 H2O	-	?

Organism

Organism	UniProt	Comment	Textmining
Sphingomonas sp. DC18	A3QQZ2	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
beta-carotene + 2 reduced acceptor + 2 O2	-	Sphingomonas sp. DC18	echinenone + 2 acceptor + 3 H2O	-	?
echinenone + 2 reduced acceptor + 2 O2	-	Sphingomonas sp. DC18	canthaxanthin + 2 acceptor + 3 H2O	-	?

Synonyms

Synonyms	Comment	Organism
CrtW	-	Sphingomonas sp. DC18

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Release 2023.1 (January 2023)