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Literature summary for 1.14.99.58 extracted from

  • Barker, K.; Barkovits, K.; Wilks, A.
    Metabolic flux of extracellular heme uptake in Pseudomonas aeruginosa is driven by the iron-regulated heme oxygenase (hemO) (2012), J. Biol. Chem., 287, 18342-18350 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) cells Pseudomonas aeruginosa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
protoheme + reduced acceptor + O2 Pseudomonas aeruginosa
-
biliverdin-IX-beta + CO + Fe2+ + acceptor + H2O
-
?
protoheme + reduced acceptor + O2 Pseudomonas aeruginosa
-
biliverdin-IX-delta + CO + Fe2+ + acceptor + H2O
-
?

Organism

Organism UniProt Comment Textmining
Pseudomonas aeruginosa
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
protoheme + reduced acceptor + O2
-
Pseudomonas aeruginosa biliverdin-IX-beta + CO + Fe2+ + acceptor + H2O
-
?
protoheme + reduced acceptor + O2
-
Pseudomonas aeruginosa biliverdin-IX-delta + CO + Fe2+ + acceptor + H2O
-
?

Synonyms

Synonyms Comment Organism
HemO
-
Pseudomonas aeruginosa

General Information

General Information Comment Organism
metabolism the catalytic action of the enzyme drives the metabolic flux of extracellular heme uptake Pseudomonas aeruginosa