Cloned (Comment) | Organism |
---|---|
- |
Mycobacterium tuberculosis |
Crystallization (Comment) | Organism |
---|---|
MhuD-diheme complex, to 1.75 A resolution, reveals two stacked hemes forming extensive contacts with residues in the active site. The solvent-exposed heme is axially liganded by His75 and is stacked planar upon the solvent-protected heme. The solvent-protected heme is coordinated by a chloride ion which is, in turn, stabilized by residue Asn7 | Mycobacterium tuberculosis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | P9WKH3 | - |
- |
Mycobacterium tuberculosis ATCC 25618 | P9WKH3 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
mycobacterial heme utilization, degrader | - |
Mycobacterium tuberculosis |
Rv3592 | - |
Mycobacterium tuberculosis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
heme | MhuD can bind heme in a 1:2 protein to heme ratio, although the MhuD-diheme complex is inactive | Mycobacterium tuberculosis |