Crystallization (Comment) | Organism |
---|---|
mutant W66Y in complex with heme and its cyanide-bound form. Heme binds to the mutant with less heme ruffling than observed for wild-type IsdI. The reduction potential of the variant (-96 mV versus standard hydrogen electrode) is similar to that of wild-type IsdI (-89 mV) | Staphylococcus aureus |
Protein Variants | Comment | Organism |
---|---|---|
W66A | Trp66 is a conserved heme pocket residue implicated in heme ruffling. Mutant is inactive | Staphylococcus aureus |
W66F | Trp66 is a conserved heme pocket residue implicated in heme ruffling. Mutant shows about half of wild-type heme degradation activity | Staphylococcus aureus |
W66L | Trp66 is a conserved heme pocket residue implicated in heme ruffling. Mutant is inactive | Staphylococcus aureus |
W66Y | Trp66 is a conserved heme pocket residue implicated in heme ruffling. Mutant shows about half of wild-type heme degradation activity | Staphylococcus aureus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Staphylococcus aureus | Q7A827 | - |
- |
Staphylococcus aureus N315 | Q7A827 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
isdG | - |
Staphylococcus aureus |