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Literature summary for 1.14.99.4 extracted from

  • Hua, Z.; Zhang, Q.; Su, T.; Lipinskas, T.W.; Ding, X.
    cDNA cloning, heterologous expression, and characterization of mouse CYP2G1, an olfactory-specific steroid hydroxylase (1997), Arch. Biochem. Biophys., 340, 208-214.
    View publication on PubMed
Search for more literature for 1.14.99.4

Cloned(Commentary)

Cloned (Comment) Organism
cDNA obtained by PCR, cloning into a baculoviral expression vector pVL1392, production of the enzyme in culturd insect cells and heterologous expression of CYP2G1 in rabbits and rats Mus musculus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0051
-
 testosterone
-
 Mus musculus
0.0076
-
 progesterone
-
 Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Mus musculus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
progesterone + NADPH + H+ + O2 Mus musculus
-
 Testosterone acetate + NADP+ + H2O
-
 ?
progesterone + NADPH + H+ + O2 Rattus norvegicus
-
 Testosterone acetate + NADP+ + H2O
-
 ?
progesterone + NADPH + H+ + O2 Oryctolagus cuniculus
-
 Testosterone acetate + NADP+ + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
 mouse, strain C57BL/6
-
Oryctolagus cuniculus
-
 rabbit
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Mus musculus
-
olfactory mucosa
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5alpha-dihydrotestosterone + NADPH + O2
-
 Oryctolagus cuniculus ?
-
 ?
androstenedione + NADPH + O2
-
 Oryctolagus cuniculus ?
-
 ?
estradiol + NADPH + O2
-
 Oryctolagus cuniculus ?
-
 ?
progesterone + NADPH + H+ + O2
-
 Mus musculus Testosterone acetate + NADP+ + H2O
-
 ?
progesterone + NADPH + H+ + O2
-
 Rattus norvegicus Testosterone acetate + NADP+ + H2O
-
 ?
progesterone + NADPH + H+ + O2
-
 Oryctolagus cuniculus Testosterone acetate + NADP+ + H2O
-
 ?
testosterone + NADPH + O2
-
 Oryctolagus cuniculus 6beta-hydroxytestosterone + NADP+ + H2O
-
 ?
testosterone + reduced acceptor + O2
-
 Mus musculus 15alpha-hydroxytestosterone + 15beta-hydroxytestosterone + 2beta-hydroxytestosterone + acceptor + H2O
-
 r

Synonyms

Synonyms Comment Organism
CYP2G1
-
 Mus musculus
CYP2G1
-
 Rattus norvegicus