Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.14.99.38 extracted from

  • Wang, J.; Zeng, L.; Zhang, L.; Guo, Z.Z.; Lu, S.F.; Ming, S.L.; Li, G.L.; Wan, B.; Tian, K.G.; Yang, G.Y.; Chu, B.B.
    Cholesterol 25-hydroxylase acts as a host restriction factor on pseudorabies virus replication (2017), J. Gen. Virol., 98, 1467-1476 .
    View publication on PubMed
Search for more literature for 1.14.99.38

Protein Variants

Protein Variants Comment Organism
H242Q/H243Q catalytically inactive Sus scrofa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cholesterol + AH2 + O2 Sus scrofa
-
 25-hydroxycholesterol + A + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
3D4/21 cell
-
 Sus scrofa
-
alveolar macrophage
-
 Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cholesterol + AH2 + O2
-
 Sus scrofa 25-hydroxycholesterol + A + H2O
-
 ?

Synonyms

Synonyms Comment Organism
CH25H
-
 Sus scrofa

Expression

Organism Comment Expression
Sus scrofa pseudorabies virus infection of porcine alveolar macrophages is attenuated by enzyme overexpression (24 h post infection) up

General Information

General Information Comment Organism
physiological function cholesterol 25-hydroxylase acts as a host restriction factor on pseudorabies virus replication Sus scrofa