Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21 cells | Plasmodium falciparum |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-(4-methoxyphenyl)-6-[[2-(4-methoxyphenyl)-3H-benzimidazol-5-yl]methyl]-1H-benzimidazole | 94.1% inhibition at 0.002 mM | Plasmodium falciparum | |
N-phenyl-1-[1-(phenylmethyl)benzimidazol-2-yl]diazenylnaphthalen-2-amine | 87.6% inhibition at 0.002 mM | Plasmodium falciparum | |
N-[4-(3,4-diethoxyphenyl)-1,2,5-oxadiazole-3-yl]-3-methylbenzamide | 92.6% inhibition at 0.002 mM | Plasmodium falciparum | |
zileuton | i.e. N-[1-(1-benzothien-2-yl)ethyl]-N-hydroxyurea | Plasmodium falciparum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
[eIF5A]-deoxyhypusine + AH2 + O2 | Plasmodium falciparum | - |
[eIF5A]-hypusine + A + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Plasmodium falciparum | - |
- |
- |
Purification (Comment) | Organism |
---|---|
Ni-NTA column chromatography, and Superdex 200 gel filtration | Plasmodium falciparum |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
[eIF5A]-deoxyhypusine + AH2 + O2 | - |
Plasmodium falciparum | [eIF5A]-hypusine + A + H2O | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 42000, SDS-PAGE | Plasmodium falciparum |
Synonyms | Comment | Organism |
---|---|---|
deoxyhypusine hydroxylase | - |
Plasmodium falciparum |
DOHH | - |
Plasmodium falciparum |