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Literature summary for 1.14.99.1 extracted from
- Different forms of vitamin E and metabolite 13-carboxychromanols inhibit cyclooxygenase-1 and its catalyzed thromboxane in platelets, and tocotrienols and 13-carboxychromanols are competitive inhibitors of 5-lipoxygenase (2022), J. Nutr. Biochem., 100, 108884 .
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| delta-tocopherol-13'-carboxychromanol | inhibits isoform Cox-1 and suppresses Cox-1 mediated formation of thromboxane in collagen-stimulated rat's platelets | Homo sapiens | |
| delta-tocotrienol | inhibits isoform Cox-1 and suppresses Cox-1 mediated formation of thromboxane in collagen-stimulated rat's platelets | Homo sapiens |  |
| delta-tocotrienol-13'-carboxychromanol | inhibits isoform Cox-1 and suppresses Cox-1 mediated formation of thromboxane in collagen-stimulated rat's platelets | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| COX-1 | - |
Homo sapiens |
| COX-2 | - |
Homo sapiens |
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