Literature summary for 1.14.99.1 extracted from

Sheldrick, E.L.; Derecka, K.; Marshall, E.; Chin, E.C.; Hodges, L.; Wathes, D.C.; Abayasekara, D.R.; Flint, A.P.
Peroxisome-proliferator-activated receptors and the control of levels of prostaglandin-endoperoxide synthase 2 by arachidonic acid in the bovine uterus (2007), Biochem. J., 406, 175-183.

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Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	the enzyme is induced by arachidonic acid up to 7.5-fold within 6 h, it is also induced by protein kinase C activators 4beta-PMA and PGF2alpha, all activation effects are blocked by PKC inhibitors, regulation, overview, protein kinase C induces PTGS2 independently of PPARs, i.e. peroxisome-proliferator-activated receptors	Bos taurus

Organism

Organism	UniProt	Comment	Textmining
Bos taurus	O62698	Holstein-Friesian cow	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
endometrium	endometrial stromal cells	Bos taurus	-
epithelium	stroma	Bos taurus	-
uterus	in the stroma of endometrial epithelium	Bos taurus	-

Synonyms

Synonyms	Comment	Organism
PG-endoperoxide synthase 2	-	Bos taurus
prostaglandin-endoperoxide synthase 2	-	Bos taurus
PTGS2	-	Bos taurus

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Release 2023.1 (January 2023)