Application | Comment | Organism |
---|---|---|
medicine | inhibition of cyclooxygenases is a mode of antiinflammatory drugs | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
for transfection of COS-7 cells | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
cyclooxygenase-1bdeltaG | mutant, in which the frame shift in the splice variant human cyclooxygenase-1b is corrected | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
aspirin | - |
Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
68000 | - |
human cyclooxygenase-1, estimated by SDS-PAGE and Western blotting, detected with a cyclooxygenase-1 antibody | Homo sapiens |
72000 | - |
human cyclooxygenase-1bdeltaG, estimated by SDS-PAGE and Western blotting, detected with a cyclooxygenase-1 and a FLAG-tag antibody | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
arachidonate + AH2 + O2 | Homo sapiens | - |
prostaglandin H2 + A + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
platelet | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
arachidonate + AH2 + O2 | - |
Homo sapiens | prostaglandin H2 + A + H2O | - |
? | |
arachidonic acid + AH2 + 2 O2 | activity assay | Homo sapiens | 6-keto-prostaglandin F1alpha + A + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
cyclooxygenase-1b | cyclooxygenase-1 splice variant | Homo sapiens |