Literature summary for 1.14.19.61 extracted from

Yasuta, T.; Okazaki, S.; Mitsui, H.; Yuhashi, K.; Ezura, H.; Minamisawa, K.
DNA sequence and mutational analysis of rhizobitoxine biosynthesis genes in Bradyrhizobium elkanii (2001), Appl. Environ. Microbiol., 67, 4999-5009 .

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
dihydrorhizobitoxine + 2 reduced ferredoxin [iron-sulfur] cluster + O2 + 2 H+	Bradyrhizobium elkanii	-	rhizobitoxine + 2 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O	-	?

Organism

Organism	UniProt	Comment	Textmining
Bradyrhizobium elkanii	Q93HS4	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
dihydrorhizobitoxine + 2 reduced ferredoxin [iron-sulfur] cluster + O2 + 2 H+	-	Bradyrhizobium elkanii	rhizobitoxine + 2 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O	-	?

Synonyms

Synonyms	Comment	Organism
rtxC	-	Bradyrhizobium elkanii

General Information

General Information	Comment	Organism
physiological function	RtxA and rRxC are necessary for rhizobitoxine production. RtxA is responsible for serinol formation and dihydrorhizobitoxine biosynthesis. RtxC encodes dihydrorhizobitoxine desaturase for the final step of rhizobitoxine production. An insertional mutant of rtxC produces serinol and dihydrorhizobitoxine but no rhizobitoxine	Bradyrhizobium elkanii

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Release 2023.1 (January 2023)