Cloned (Comment) | Organism |
---|---|
gene fat-2, sequence comparison and phylogenetic tree, expression in Saccharomyces cerevisiae strain S288C | Caenorhabditis elegans |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Caenorhabditis elegans | G5EGA5 | gene fat-2 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
linoleate + AH2 + O2 | - |
Caenorhabditis elegans | crepenynate + A + 2 H2O | - |
? | |
additional information | the enzyme is able to desaturate C16 and C18 fatty acids. When recombinantly expressed in yeast cells, the enzyme can also catalyze DELTA15 desaturation. The recombinant enzyme can also produce C14:2DELTA9,12, C15:2DELTA9,12, C17:2DELTA9,12, and C18:4DELTA6,9,12,15 when C14:1DELTA9, C15:1DELTA9, C17:1DELTA9, and C18:3DELTA6,9,12 substrates are available in yeast cells, product mass spectrometry analysis | Caenorhabditis elegans | ? | - |
? | |
oleate + AH2 + O2 | recombinant enzyme | Caenorhabditis elegans | linoleic acid + linolenic acid + A + 2 H2O | - |
? | |
palmitoleic acid + O2 | recombinant enzyme | Caenorhabditis elegans | hexadecadienoic acid + hexadecatrienoic acid + A + 2 H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
DELTA12-desaturase | - |
Caenorhabditis elegans |
FAT-2 | - |
Caenorhabditis elegans |
fatty acid DELTA12-desaturase | - |
Caenorhabditis elegans |