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Literature summary for 1.14.19.30 extracted from

  • Shimizu, S.; Kawashima, H.; Akimoto, K.; Shinmen, Y.; Sugano, H.; Yamada, H.
    Inhibition of DELTA5-desaturase in polyunsaturated fatty acid biosynthesis by (-)-asarinin and (-)-epiasarinin (1992), Phytochemistry, 31, 757-760.
No PubMed abstract available
Search for more literature for 1.14.19.30

Inhibitors

Inhibitors Comment Organism Structure
(+)-episesamin specific inhibitor Rattus norvegicus
(+)-sesamin specific inhibitor Rattus norvegicus
(+)-sesaminol specific inhibitor Rattus norvegicus
(+)-sesamolin specific inhibitor Rattus norvegicus
(-)-asarinin non-competitive inhibitor Rattus norvegicus
(-)-epiasarinin non-competitive inhibitor Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Rattus norvegicus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
dihomo-gamma-linolenic acid + ferrocytochrome b5 + O2 + H+ Rattus norvegicus
-
 arachidonic acid + ferricytochrome b5 + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dihomo-gamma-linolenic acid + ferrocytochrome b5 + O2 + H+
-
 Rattus norvegicus arachidonic acid + ferricytochrome b5 + H2O
-
 ?

Synonyms

Synonyms Comment Organism
DELTA5-desaturase
-
 Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
cytochrome b5
-
 Rattus norvegicus

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.28
-
 (-)-asarinin pH and temperature not specified in the publication Rattus norvegicus
0.71
-
 (-)-epiasarinin pH and temperature not specified in the publication Rattus norvegicus