Literature summary for 1.14.19.30 extracted from

Peng, K.; Zheng, C.; Xue, J.; Chen, X.; Yang, W.; Liu, J.; Bai, W.; Li, H.
Delta 5 fatty acid desaturase upregulates the synthesis of polyunsaturated fatty acids in the marine diatom Phaeodactylum tricornutum (2014), J. Agric. Food Chem., 62, 8773-8776.

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Cloned(Commentary)

Cloned (Comment)	Organism
overexpressed in Phaeodactylum tricornutum	Phaeodactylum tricornutum

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
(8Z,11Z,14Z)-icosa-8,11,14-trienoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+	Phaeodactylum tricornutum	-	(5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-tetraenoyl-[glycerolipid] + ferricytochrome b5 + H2O	-	?
(8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+	Phaeodactylum tricornutum	-	(5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoyl-[glycerolipid] + ferricytochrome b5 + H2O	-	?

Organism

Organism	UniProt	Comment	Textmining
Phaeodactylum tricornutum	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(8Z,11Z,14Z)-icosa-8,11,14-trienoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+	-	Phaeodactylum tricornutum	(5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-tetraenoyl-[glycerolipid] + ferricytochrome b5 + H2O	-	?
(8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+	-	Phaeodactylum tricornutum	(5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoyl-[glycerolipid] + ferricytochrome b5 + H2O	-	?

Synonyms

Synonyms	Comment	Organism
D5b	-	Phaeodactylum tricornutum
delta 5 desaturase	-	Phaeodactylum tricornutum
DELTA 5 fatty acid desaturase	-	Phaeodactylum tricornutum

Cofactor

Cofactor	Comment	Organism	Structure
cytochrome b5	-	Phaeodactylum tricornutum

General Information

General Information	Comment	Organism
metabolism	delta 5 desaturase plays a role in the eicosapentaenoic acid biosynthetic pathway	Phaeodactylum tricornutum

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Release 2023.1 (January 2023)