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Literature summary for 1.14.19.30 extracted from

  • Kumon, Y.; Kamisaka, Y.; Tomita, N.; Kimura, K.; Uemura, H.; Yokochi, T.; Yokoyama, R.; Honda, D.
    Isolation and characterization of a DELTA5-desaturase from Oblongichytrium sp. (2008), Biosci. Biotechnol. Biochem., 72, 2224-2227.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Saccharomyces cerevisiae strain BY4741 Oblongichytrium sp. SEK 347

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(8Z,11Z,14Z)-eicosa-8,11,14-trienoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ Oblongichytrium sp. SEK 347
-
(5Z,8Z,11Z,14Z)-eicosatetra-5,8,11,14-tetraenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
?
(8Z,11Z,14Z,17Z)-eicosa-8,11,14,17-tetraenoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ Oblongichytrium sp. SEK 347 best substrate (5Z,8Z,11Z,14Z,17Z)-eicosa-5,8,11,14,17-pentaenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
?

Organism

Organism UniProt Comment Textmining
Oblongichytrium sp. SEK 347 B5MFC9
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(8Z,11Z,14Z)-eicosa-8,11,14-trienoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+
-
Oblongichytrium sp. SEK 347 (5Z,8Z,11Z,14Z)-eicosatetra-5,8,11,14-tetraenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
?
(8Z,11Z,14Z,17Z)-eicosa-8,11,14,17-tetraenoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ best substrate Oblongichytrium sp. SEK 347 (5Z,8Z,11Z,14Z,17Z)-eicosa-5,8,11,14,17-pentaenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
?
eicosa-11,14,17-trienoate + acceptor + O2 + H+
-
Oblongichytrium sp. SEK 347 eicosa-5,11,14,17-tetraenoate + ? i.e. juniperoate ?
eicosa-11,14-dienoate + acceptor + O2 + H+
-
Oblongichytrium sp. SEK 347 eicosa-5,11,14-trienoate + ? i.e. sciadonoate ?
additional information no activity with 18:2(DELTA9,12), 18:3n-3(DELTA9,12,15), or 22:5n-3(DELTA7,11,13,16,19) Oblongichytrium sp. SEK 347 ?
-
?

Synonyms

Synonyms Comment Organism
DELTA5-desaturase
-
Oblongichytrium sp. SEK 347

Cofactor

Cofactor Comment Organism Structure
cytochrome b5
-
Oblongichytrium sp. SEK 347