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Literature summary for 1.14.19.30 extracted from

  • Tavares, S.; Grotkjaer, T.; Obsen, T.; Haslam, R.; Napier, J.; Gunnarsson, N.
    Metabolic engineering of Saccharomyces cerevisiae for production of eicosapentaenoic acid, using a novel DELTA5-desaturase from Paramecium tetraurelia (2011), Appl. Environ. Microbiol., 77, 1854-1861.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.14.19.30

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Saccharoymces cerevisiae strain CEN.PK 113-5D Leishmania major
expressed in Saccharoymces cerevisiae strain CEN.PK 113-5D Paramecium tetraurelia
expressed in Saccharoymces cerevisiae strain CEN.PK 113-5D Mortierella alpina
expressed in Saccharoymces cerevisiae strain CEN.PK 113-5D Ostreococcus tauri
expressed in Saccharoymces cerevisiae strain CEN.PK 113-5D Ostreococcus sp. 'lucimarinus'

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(8Z,11Z,14Z)-icosa-8,11,14-trienoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ Leishmania major
-
 (5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-tetraenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?
(8Z,11Z,14Z)-icosa-8,11,14-trienoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ Paramecium tetraurelia
-
 (5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-tetraenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?
(8Z,11Z,14Z)-icosa-8,11,14-trienoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ Mortierella alpina
-
 (5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-tetraenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?
(8Z,11Z,14Z)-icosa-8,11,14-trienoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ Ostreococcus tauri
-
 (5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-tetraenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?
(8Z,11Z,14Z)-icosa-8,11,14-trienoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ Ostreococcus sp. 'lucimarinus'
-
 (5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-tetraenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?
(8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ Leishmania major
-
 (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?
(8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ Paramecium tetraurelia
-
 (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?
(8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ Mortierella alpina
-
 (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?
(8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ Ostreococcus tauri
-
 (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?
(8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ Ostreococcus sp. 'lucimarinus'
-
 (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Leishmania major
-
-
-
Mortierella alpina
-
-
-
Ostreococcus sp. 'lucimarinus'
-
-
-
Ostreococcus tauri
-
-
-
Paramecium tetraurelia
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(8Z,11Z,14Z)-icosa-8,11,14-trienoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+
-
 Leishmania major (5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-tetraenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?
(8Z,11Z,14Z)-icosa-8,11,14-trienoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+
-
 Paramecium tetraurelia (5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-tetraenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?
(8Z,11Z,14Z)-icosa-8,11,14-trienoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+
-
 Mortierella alpina (5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-tetraenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?
(8Z,11Z,14Z)-icosa-8,11,14-trienoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+
-
 Ostreococcus tauri (5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-tetraenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?
(8Z,11Z,14Z)-icosa-8,11,14-trienoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+
-
 Ostreococcus sp. 'lucimarinus' (5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-tetraenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?
(8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+
-
 Leishmania major (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?
(8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+
-
 Paramecium tetraurelia (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?
(8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+
-
 Mortierella alpina (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?
(8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+
-
 Ostreococcus tauri (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?
(8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+
-
 Ostreococcus sp. 'lucimarinus' (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?

Synonyms

Synonyms Comment Organism
D5D
-
 Leishmania major
D5D
-
 Paramecium tetraurelia
D5D
-
 Mortierella alpina
D5D
-
 Ostreococcus tauri
D5D
-
 Ostreococcus sp. 'lucimarinus'
DELTA5 desaturase
-
 Leishmania major
DELTA5 desaturase
-
 Paramecium tetraurelia
DELTA5 desaturase
-
 Mortierella alpina
DELTA5 desaturase
-
 Ostreococcus tauri
DELTA5 desaturase
-
 Ostreococcus sp. 'lucimarinus'

Cofactor

Cofactor Comment Organism Structure
cytochrome b5
-
 Leishmania major
cytochrome b5
-
 Paramecium tetraurelia
cytochrome b5
-
 Mortierella alpina
cytochrome b5
-
 Ostreococcus tauri
cytochrome b5
-
 Ostreococcus sp. 'lucimarinus'