Literature summary for 1.14.19.3 extracted from

Park, H.G.; Kothapalli, K.S.D.; Park, W.J.; DeAllie, C.; Liu, L.; Liang, A.; Lawrence, P.; Brenna, J.T.
Palmitic acid (16 0) competes with omega-6 linoleic and omega-3 alpha-linolenic acids for FADS2 mediated DELTA6-desaturation (2016), Biochim. Biophys. Acta, 1861, 91-97 .

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Cloned(Commentary)

Cloned (Comment)	Organism
expression in MCF7 cells	Papio anubis

Organism

Organism	UniProt	Comment	Textmining
Papio anubis	B8R1K0	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	the FADS2 product introduces a double bond at the DELTA6, DELTA4 and DELTA8 positions by acting on at least ten substrates, including fatty acids 16:0, 18:2n-6, and 18:3n-3. MCF7 cells stably transformed with FADS2 biosynthesizes fatty acid 16:1n-10 from exogenous fatty acid 16:0, fatty acid 18:4n-3 from fatty acid 18:3n-3, fatty acid 18:3n-6 from fatty acid 18:2n-6, fatty acid 18:2n-9 from fatty acid 18:1n-9, fatty acid 24:6n-3 from fatty acid 24:5n-3 and fatty acid 24:5n-6 from fatty acid 24:4n-6	Papio anubis	?	-	?

Synonyms

Synonyms	Comment	Organism
FADS2	-	Papio anubis

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Release 2023.1 (January 2023)