Cloned (Comment) | Organism |
---|---|
expressed as chimera protein with DELTA6 fatty acid desaturase in Saccharomyces cervisiae | Borago officinalis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(4R)-4-hydroxysphinganine ceramide + ferrocytochrome b5 + O2 + H+ | Borago officinalis | 39.8% conversion rate | (4R,8E)-4-hydroxysphing-8-enine ceramide + ferricytochrome b5 + H2O | - |
? | |
(4R)-4-hydroxysphinganine ceramide + ferrocytochrome b5 + O2 + H+ | Borago officinalis | 7.5% conversion rate | (4R,8Z)-4-hydroxysphing-8-enine ceramide + ferricytochrome b5 + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Borago officinalis | Q9FR82 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(4R)-4-hydroxysphinganine ceramide + ferrocytochrome b5 + O2 + H+ | 39.8% conversion rate | Borago officinalis | (4R,8E)-4-hydroxysphing-8-enine ceramide + ferricytochrome b5 + H2O | - |
? | |
(4R)-4-hydroxysphinganine ceramide + ferrocytochrome b5 + O2 + H+ | 7.5% conversion rate | Borago officinalis | (4R,8Z)-4-hydroxysphing-8-enine ceramide + ferricytochrome b5 + H2O | - |
? | |
additional information | no activity with palmitoleic acid, linoleic acid, and alpha-linolenic acid | Borago officinalis | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
DELTA8-sphingolipid desaturase | - |
Borago officinalis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
cytochrome b5 | - |
Borago officinalis |