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Literature summary for 1.14.19.20 extracted from

  • Grinstead, G.F.; Gaylor, J.L.
    Total enzymic synthesis of cholesterol from 4,4,14alpha-trimethyl-5alpha-cholesta-8,24-dien-3beta-ol. Solubilization, resolution, and reconstitution of DELTA 7-sterol 5-desaturase (1982), J. Biol. Chem., 257, 13937-13944.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
Rattus norvegicus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5alpha-cholest-7-en-3beta-ol + 2 ferrocytochrome b5 + O2 + 2 H+ Rattus norvegicus cholesterol biosynthesis cholesta-5,7-dien-3beta-ol + 2 ferricytochrome b5 + 2 H2O
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5alpha-cholest-7-en-3beta-ol + 2 ferrocytochrome b5 + O2 + 2 H+ i.e. lathosterol Rattus norvegicus cholesta-5,7-dien-3beta-ol + 2 ferricytochrome b5 + 2 H2O
-
?
5alpha-cholest-7-en-3beta-ol + 2 ferrocytochrome b5 + O2 + 2 H+ cholesterol biosynthesis Rattus norvegicus cholesta-5,7-dien-3beta-ol + 2 ferricytochrome b5 + 2 H2O
-
?

Cofactor

Cofactor Comment Organism Structure
NAD(P)H
-
Rattus norvegicus