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Literature summary for 1.14.19.18 extracted from

  • Oura, T.; Kajiwara, S.
    Disruption of the sphingolipid DELTA8-desaturase gene causes a delay in morphological changes in Candida albicans (2008), Microbiology, 154, 3795-3803.
    View publication on PubMed
Search for more literature for 1.14.19.18

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(4E)-sphing-4-enine ceramide + ferrocytochrome b5 + O2 + H+ Candida albicans
-
 (4E,8E)-sphing-4,8-dienine ceramide + ferricytochrome b5 + H2O
-
 ?
(4E)-sphing-4-enine ceramide + ferrocytochrome b5 + O2 + H+ Candida albicans TUA6
-
 (4E,8E)-sphing-4,8-dienine ceramide + ferricytochrome b5 + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Candida albicans
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(4E)-sphing-4-enine ceramide + ferrocytochrome b5 + O2 + H+
-
 Candida albicans (4E,8E)-sphing-4,8-dienine ceramide + ferricytochrome b5 + H2O
-
 ?
(4E)-sphing-4-enine ceramide + ferrocytochrome b5 + O2 + H+
-
 Candida albicans TUA6 (4E,8E)-sphing-4,8-dienine ceramide + ferricytochrome b5 + H2O
-
 ?

Synonyms

Synonyms Comment Organism
DELTA8-sphingolipid desaturase
-
 Candida albicans
SLD
-
 Candida albicans

Cofactor

Cofactor Comment Organism Structure
cytochrome b5
-
 Candida albicans

General Information

General Information Comment Organism
physiological function disruption of the DELTA8-sphingolipid desaturase gene leads to a decreased hyphal growth rate compared with the wild type strain Candida albicans