Inhibitors | Comment | Organism | Structure |
---|---|---|---|
cytochrome c | - |
Rattus norvegicus | |
cytochrome c | very low inhibitor concentrations of 10 mM lead to an almost complete inhibition of the SCD benzamidoxime reductase activity of porcine adipose tissue microsome | Sus scrofa | |
p-hydroxymercuribenzoate | - |
Rattus norvegicus | |
p-hydroxymercuribenzoate | potent inhibitor of the SCD benzamidoxime reductase activity of porcine adipose tissue microsomes | Sus scrofa | |
potassium cyanide | - |
Rattus norvegicus | |
potassium cyanide | supplementation of potassium cyanide leads to a 65% inhibition of the microsomal benzamidoxime reductase activity of SCD in porcine adipose tissue | Sus scrofa | |
potassium hexacyanoferrate | - |
Rattus norvegicus | |
potassium hexacyanoferrate | - |
Sus scrofa | |
stearoyl-CoA | inhibits SCD activity in concentrations greater than 0.05 mM | Rattus norvegicus | |
stearoyl-CoA | inhibits SCD activity in concentrations greater than 0.05 mM | Sus scrofa |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Rattus norvegicus | - |
- |
microsome | - |
Sus scrofa | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
37000 | - |
SDS-PAGE | Rattus norvegicus |
41000 | - |
SDS-PAGE | Sus scrofa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Sus scrofa | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
- |
Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adipose tissue | - |
Rattus norvegicus | - |
adipose tissue | - |
Sus scrofa | - |
liver | - |
Rattus norvegicus | - |
liver | - |
Sus scrofa | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-hydroxy-benzenecarboximidamide + NADH + H+ + O2 | - |
Rattus norvegicus | benzamidine + NAD+ + H2O | - |
? | |
N-hydroxy-benzenecarboximidamide + NADH + H+ + O2 | - |
Sus scrofa | benzamidine + NAD+ + H2O | - |
? | |
stearoyl-CoA + NADH + H+ + O2 | - |
Rattus norvegicus | oleoyl-CoA + NAD+ + H2O | - |
? | |
stearoyl-CoA + NADH + H+ + O2 | - |
Sus scrofa | oleoyl-CoA + NAD+ + H2O | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 37000, SDS-PAGE | Rattus norvegicus |
Synonyms | Comment | Organism |
---|---|---|
SCD | - |
Rattus norvegicus |
SCD | - |
Sus scrofa |
stearoyl-CoA desaturase | - |
Rattus norvegicus |
stearoyl-CoA desaturase | - |
Sus scrofa |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0000019 | - |
N-hydroxy-benzenecarboximidamide | at 37°C | Sus scrofa |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | - |
Rattus norvegicus | |
NADH | - |
Sus scrofa |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0018 | - |
at 37°C | Sus scrofa | cytochrome c | |
0.2 | - |
at 37°C | Sus scrofa | stearoyl-CoA | |
0.229 | - |
at 37°C | Sus scrofa | potassium hexacyanoferrate | |
0.3 | - |
at 37°C | Sus scrofa | potassium cyanide |