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Literature summary for 1.14.19.1 extracted from

  • Sampath, H.; Miyazaki, M.; Dobrzyn, A.; Ntambi, J.M.
    Stearoyl-CoA desaturase-1 mediates the pro-lipogenic effects of dietary saturated fat (2007), J. Biol. Chem., 282, 2483-2493.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome from liver, 40% increase in enzyme activity in hepatic microsomes in tristearin-fed compared with trioleate-fed mice Mus musculus
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Organism

Organism UniProt Comment Textmining
Mus musculus
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129 SvEv wild-type and Sc1-/- mice
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Source Tissue

Source Tissue Comment Organism Textmining
liver 5fold higher expression and 40% increase in enzyme activity in hepatic microsomes in tristearin-fed compared with trioleate-fed mice Mus musculus
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Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
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40% increase in enzyme activity in hepatic microsomes in tristearin-fed compared with trioleate-fed mice Mus musculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
stearoyl-CoA + NADH + O2 Scd-/- and wild-type mice are fed with 20% high fat diets, fat-free basal mix is supplemented with 20% by weight of tristearin or triolein and 1% by weight corn oil Mus musculus oleoyl-CoA + NAD+ + H2O
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Synonyms

Synonyms Comment Organism
SCD1
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Mus musculus