Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.14.18.3 extracted from

  • Larsen, O.; Karlsen, O.A.
    Transcriptomic profiling of Methylococcus capsulatus (Bath) during growth with two different methane monooxygenases (2016), MicrobiologyOpen, 5, 254-267 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.14.18.3

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Methylococcus capsulatus 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
methane + quinol + O2 Methylococcus capsulatus
-
 methanol + quinone + H2O
-
 ?
methane + quinol + O2 Methylococcus capsulatus Methylococcus capsulatus (Bath) is a methanotroph that possesses both a membrane-embedded (pMMO) and a soluble methane monooxygenase (sMMO). Major changes takes place in the respiratory chain between pMMO- and sMMO-producing cells. Quinones are predominantly used as the electron donors for methane oxidation by pMMO. During production of particulate methane monooxygenase, the majority of quinones are directed to methane oxidation methanol + quinone + H2O
-
 ?
methane + quinol + O2 Methylococcus capsulatus Bath Methylococcus capsulatus (Bath) is a methanotroph that possesses both a membrane-embedded (pMMO) and a soluble methane monooxygenase (sMMO). Major changes takes place in the respiratory chain between pMMO- and sMMO-producing cells. Quinones are predominantly used as the electron donors for methane oxidation by pMMO. During production of particulate methane monooxygenase, the majority of quinones are directed to methane oxidation methanol + quinone + H2O
-
 ?
methane + quinol + O2 Methylococcus capsulatus Bath
-
 methanol + quinone + H2O
-
 ?
methane + quinol + O2 Methylococcus capsulatus Bath. Methylococcus capsulatus (Bath) is a methanotroph that possesses both a membrane-embedded (pMMO) and a soluble methane monooxygenase (sMMO). Major changes takes place in the respiratory chain between pMMO- and sMMO-producing cells. Quinones are predominantly used as the electron donors for methane oxidation by pMMO. During production of particulate methane monooxygenase, the majority of quinones are directed to methane oxidation methanol + quinone + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Methylococcus capsulatus
-
-
-
Methylococcus capsulatus G1UBD1 AND Q607G3 alpha- and beta-subunits
-
Methylococcus capsulatus Bath G1UBD1 AND Q607G3 alpha- and beta-subunits
-
Methylococcus capsulatus Bath.
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information transcriptomic profiling of particulate MMO is used to investigate the gene expression pattern in Methylococcus capsulatus during methanotrophic growth in the presence and absence of copper, overview Methylococcus capsulatus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
methane + quinol + O2
-
 Methylococcus capsulatus methanol + quinone + H2O
-
 ?
methane + quinol + O2 Methylococcus capsulatus (Bath) is a methanotroph that possesses both a membrane-embedded (pMMO) and a soluble methane monooxygenase (sMMO). Major changes takes place in the respiratory chain between pMMO- and sMMO-producing cells. Quinones are predominantly used as the electron donors for methane oxidation by pMMO. During production of particulate methane monooxygenase, the majority of quinones are directed to methane oxidation Methylococcus capsulatus methanol + quinone + H2O
-
 ?
methane + quinol + O2 Methylococcus capsulatus (Bath) is a methanotroph that possesses both a membrane-embedded (pMMO) and a soluble methane monooxygenase (sMMO). Major changes takes place in the respiratory chain between pMMO- and sMMO-producing cells. Quinones are predominantly used as the electron donors for methane oxidation by pMMO. During production of particulate methane monooxygenase, the majority of quinones are directed to methane oxidation Methylococcus capsulatus Bath methanol + quinone + H2O
-
 ?
methane + quinol + O2
-
 Methylococcus capsulatus Bath methanol + quinone + H2O
-
 ?
methane + quinol + O2 Methylococcus capsulatus (Bath) is a methanotroph that possesses both a membrane-embedded (pMMO) and a soluble methane monooxygenase (sMMO). Major changes takes place in the respiratory chain between pMMO- and sMMO-producing cells. Quinones are predominantly used as the electron donors for methane oxidation by pMMO. During production of particulate methane monooxygenase, the majority of quinones are directed to methane oxidation Methylococcus capsulatus Bath. methanol + quinone + H2O
-
 ?

Synonyms

Synonyms Comment Organism
membrane-embedded methane monooxygenase
-
 Methylococcus capsulatus
pMMO
-
 Methylococcus capsulatus

Cofactor

Cofactor Comment Organism Structure
quinol quinone is predominantly used by pMMO in order to sustain its activity Methylococcus capsulatus

General Information

General Information Comment Organism
metabolism during production of particulate methane monooxygenase, the majority of quinones are directed to methane oxidation Methylococcus capsulatus
metabolism the enzyme expresses the soluble enzyme form under copper limitation, and the membrane-bound particulate MMO at high copper-to-biomass ratio, analysis of the mechanism of the copper switch. Transcriptomic profiling of particulate MMO and soluble MMO, EC 1.14.13.25, using Methylococcus capsulatus DNA microarrays. 137 ORFs are found to be differentially expressed between cells producing sMMO and pMMO, while only minor differences in gene expression are observed between the pMMO-producing cultures. Of these, 87 genes are upregulated during sMMO-producing cells, i.e. during copper-limited growth. Major changes takes place in the respiratory chain between pMMO-and sMMO-producing cells, and quinone are predominantly used as the electron donors for methane oxidation by pMMO. Proposed pathway of methane oxidation in Methylococcus capsulatus cells producing either sMMO or pMMO, overview Methylococcus capsulatus