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Literature summary for 1.14.18.2 extracted from

  • Shaw, L.; Schneckenburger, P.; Schlenzka, W.; Carlsen, J.; Christiansen, K.; Juergensen, D.; Schauer, R.
    CMP-N-acetylneuraminic acid hydroxylase from mouse liver and pig submandibular glands. Interaction with membrane-bound and soluble cytochrome b5-dependent electron transport chains (1994), Eur. J. Biochem., 219, 1001-1011.
    View publication on PubMed
Search for more literature for 1.14.18.2

Inhibitors

Inhibitors Comment Organism Structure
anti-(rat cytochrome b5) antiserum
-
 Mus musculus
anti-(rat cytochrome b5) antiserum
-
 Sus scrofa

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
56000
-
 gel filtration Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
CMP-N-acetylneuraminate + NADH + O2 Mus musculus
-
 CMP-N-glycoloylneuraminate + NAD+ + H2O
-
 ?
CMP-N-acetylneuraminate + NADH + O2 Sus scrofa
-
 CMP-N-glycoloylneuraminate + NAD+ + H2O
-
 ?
CMP-N-acetylneuraminate + NADH + O2 Bos taurus
-
 CMP-N-glycoloylneuraminate + NAD+ + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Mus musculus
-
-
-
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Mus musculus
-
liver
-
 Sus scrofa
-
submandibular gland
-
 Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CMP-N-acetylneuraminate + ferrocytochrome b5 + O2 pure hydrophilic cytochrome b5 interacts more effectively with the hydroxylase than isolated amphiphytic cytochrome b5 Mus musculus CMP-N-glycoloylneuraminate + ferricytrochrome b5 + H2O
-
 ?
CMP-N-acetylneuraminate + ferrocytochrome b5 + O2 pure hydrophilic cytochrome b5 interacts more effectively with the hydroxylase than isolated amphiphytic cytochrome b5 Sus scrofa CMP-N-glycoloylneuraminate + ferricytrochrome b5 + H2O
-
 ?
CMP-N-acetylneuraminate + NADH + O2
-
 Mus musculus CMP-N-glycoloylneuraminate + NAD+ + H2O
-
 ?
CMP-N-acetylneuraminate + NADH + O2
-
 Sus scrofa CMP-N-glycoloylneuraminate + NAD+ + H2O
-
 ?
CMP-N-acetylneuraminate + NADH + O2
-
 Bos taurus CMP-N-glycoloylneuraminate + NAD+ + H2O
-
 ?

Cofactor

Cofactor Comment Organism Structure
ferrocytochrome b5 pure hydrophilic cytochrome b5 interacts more effectively with the hydroxylase than isolated amphiphytic cytochrome b5 Mus musculus
ferrocytochrome b5 pure hydrophilic cytochrome b5 interacts more effectively with the hydroxylase than isolated amphiphytic cytochrome b5 Sus scrofa
NADH
-
 Mus musculus
NADH
-
 Sus scrofa
NADH
-
 Bos taurus