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Literature summary for 1.14.18.10 extracted from

  • Singh, A.; Jindal, S.; Longchar, B.; Khan, F.; Gupta, V.
    Overexpression of Artemisia annua sterol C-4 methyl oxidase gene, AaSMO1, enhances total sterols and improves tolerance to dehydration stress in tobacco (2015), Plant Cell Tissue Organ Cult., 121, 167-181 .
No PubMed abstract available

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Nicotiana tabacum cultivar Xanthi leaves Artemisia annua

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
Artemisia annua 5783
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
24-methylidenecycloartanol + 6 ferrocytochrome b5 + 3 O2 + 6 H+ Artemisia annua overall reaction 3beta-hydroxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-ene-4alpha-carboxylate + 6 ferricytochrome b5 + 4 H2O
-
?

Organism

Organism UniProt Comment Textmining
Artemisia annua A0A0A6YZ36 variant CIM-Arogya
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
24-methylidenecycloartanol + 6 ferrocytochrome b5 + 3 O2 + 6 H+ overall reaction Artemisia annua 3beta-hydroxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-ene-4alpha-carboxylate + 6 ferricytochrome b5 + 4 H2O
-
?

Subunits

Subunits Comment Organism
? x * 35440, calculated from amino acid sequence Artemisia annua

Synonyms

Synonyms Comment Organism
SMO1
-
Artemisia annua
sterol C-4 methyl oxidase
-
Artemisia annua
sterol-4alpha-methyl-oxidase
-
Artemisia annua

Cofactor

Cofactor Comment Organism Structure
cytochrome b5
-
Artemisia annua

pI Value

Organism Comment pI Value Maximum pI Value
Artemisia annua calculated from amino acid sequence
-
7.8

Expression

Organism Comment Expression
Artemisia annua enzyme expression significantly gets down-regulated (up to about 5fold) under salinity conditions with 400 mM NaCl. The enzyme expression is clearly down-regulated after 3 h treatment with 150 mg/ml chitosan or after 6 h treatment with 0.3 mM methyl jasmonate or after 1.5 h treatment with 1 mM salicylic acid or after 1.5 h treatment with 1 mM trans-cinnamic acid down
Artemisia annua transcript levels of the enzyme are consistently increased upon 0.01 mM abscisic acid or 0.1 mM gibberellic acid treatment and induced to more than 2fold relative to the control seedlings. Osmotic/dehydration stress with 400 mM mannitol markedly induces the transcript levels during 6-9 h of treatment and decreases then after up

General Information

General Information Comment Organism
physiological function enzyme overexpression enhances total sterols and improves tolerance to osmotic/dehydration stress in transgenic tobacco plants Artemisia annua