Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-phenyl-2-butanol | a reversible, potent inhibitor of tyrosinase, mixed-type inhibitor fothe monophenoase activity and noncompetitive-type inhibitor for the diphenolase activity | Agaricus bisporus | |
benzylacetone | a reversible, potent inhibitor of tyrosinase, mixed-type inhibitor | Agaricus bisporus | |
benzylideneacetone | a reversible, potent inhibitor of tyrosinase, mixed-type inhibitor | Agaricus bisporus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Cu2+ | a copper-containing enzyme | Agaricus bisporus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 L-dopa + O2 | Agaricus bisporus | - |
2 dopaquinone + 2 H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Agaricus bisporus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
commercial preparation | - |
Agaricus bisporus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 L-dopa + O2 | - |
Agaricus bisporus | 2 dopaquinone + 2 H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
mushroom tyrosinase | - |
Agaricus bisporus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | inhibition kinetics, type, and constants, and inhibition mechanism of benzylideneacetone, benzylacetone, and 4-phenyl-2-butanol, overview | Agaricus bisporus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.6 | - |
inhibition of diphenolase activity of the enzyme, pH and temperature not specified in the publication | Agaricus bisporus | benzylacetone | |
0.8 | - |
inhibition of diphenolase activity of the enzyme, pH and temperature not specified in the publication | Agaricus bisporus | 4-phenyl-2-butanol | |
1.1 | - |
inhibition of monophenolase activity of the enzyme, pH and temperature not specified in the publication | Agaricus bisporus | 4-phenyl-2-butanol | |
1.5 | - |
inhibition of monophenolase activity of the enzyme, pH and temperature not specified in the publication | Agaricus bisporus | benzylideneacetone | |
2 | - |
inhibition of diphenolase activity of the enzyme, pH and temperature not specified in the publication | Agaricus bisporus | benzylideneacetone | |
2.8 | - |
inhibition of monophenolase activity of the enzyme, pH and temperature not specified in the publication | Agaricus bisporus | benzylacetone |
General Information | Comment | Organism |
---|---|---|
additional information | tyrosinase is a kind of multiple functional oxidase containing di-copper catalytic core | Agaricus bisporus |