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Literature summary for 1.14.18.1 extracted from

  • Chai, W.M.; Wei, M.K.; Wang, R.; Deng, R.G.; Zou, Z.R.; Peng, Y.Y.
    Avocado proanthocyanidins as a source of tyrosinase inhibitors structure characterization, inhibitory activity, and mechanism (2015), J. Agric. Food Chem., 63, 7381-7387 .
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
afzelechin
-
Agaricus bisporus
catechin
-
Agaricus bisporus
epiafzelechin
-
Agaricus bisporus
epicatechin
-
Agaricus bisporus
epigallocatechin
-
Agaricus bisporus
gallocatechin
-
Agaricus bisporus
additional information avocado proanthocyanidins, from Persea americana fruits, are a source of tyrosinase inhibitors, they are reversible and competitive inhibitors, structure-activity relationships, and inhibition mechanism, overview. Ligand structure analysis by mass spectroscopy Agaricus bisporus
procyanidin
-
Agaricus bisporus
prodelphindin
-
Agaricus bisporus
propelargonidin
-
Agaricus bisporus

Metals/Ions

Metals/Ions Comment Organism Structure
Cu2+ a copper-containing enzyme Agaricus bisporus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2 L-dopa + O2 Agaricus bisporus
-
2 dopaquinone + 2 H2O
-
?
tyrosine + O2 Agaricus bisporus
-
dopaquinone + H2O
-
?

Organism

Organism UniProt Comment Textmining
Agaricus bisporus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
commercial preparation
-
Agaricus bisporus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 L-dopa + O2
-
Agaricus bisporus 2 dopaquinone + 2 H2O
-
?
tyrosine + O2
-
Agaricus bisporus dopaquinone + H2O
-
?

Synonyms

Synonyms Comment Organism
mushroom tyrosinase
-
Agaricus bisporus