Inhibitors | Comment | Organism | Structure |
---|---|---|---|
6-hydroxyapigenin | 5,6,7-trihydroxyflavone, high inhibitory effects on tyrosinase. Acts as a cofactor to monophenolase | Agaricus bisporus | |
6-hydroxygalangin | 5,6,7-trihydroxyflavone, high inhibitory effects on tyrosinase. Acts as a cofactor to monophenolase | Agaricus bisporus | |
6-hydroxykaempferol | 5,6,7-trihydroxyflavone, high inhibitory effects on tyrosinase. Acts as a cofactor to monophenolase. competitive inhibitor | Agaricus bisporus | |
baicalein | 5,6,7-trihydroxyflavone, high inhibitory effects on tyrosinase. Acts as a cofactor to monophenolase | Agaricus bisporus | |
kaempferol | - |
Agaricus bisporus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
copper | - |
Agaricus bisporus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Agaricus bisporus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
commercial preparation | - |
Agaricus bisporus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
3320 | - |
- |
Agaricus bisporus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-dopa + 1/2 O2 | - |
Agaricus bisporus | L-dopaquinone + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
tyrosinase | - |
Agaricus bisporus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.148 | - |
6-hydroxykaempferol | a competitive inhibitor of tyrosinase, L-DOPA as a substrate | Agaricus bisporus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.124 | - |
- |
Agaricus bisporus | 6-hydroxykaempferol | |
0.182 | - |
- |
Agaricus bisporus | 6-hydroxygalangin | |
0.193 | - |
- |
Agaricus bisporus | 6-hydroxyapigenin | |
0.262 | - |
- |
Agaricus bisporus | kaempferol | |
0.273 | - |
- |
Agaricus bisporus | baicalein |