Any feedback?
Literature summary for 1.14.18.1 extracted from
- Kinetic study of monophenol and o-diphenol binding to oxytyrosinase (2005), J. Mol. Catal. B, 32, 185-192.
No PubMed abstract available
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | detailed kinetics, overview | Neurospora crassa | |
| additional information | - |
additional information | detailed kinetics, overview | Agaricus bisporus | |
| additional information | - |
additional information | detailed kinetics, overview | Streptomyces glaucescens | |
| additional information | - |
additional information | detailed kinetics, overview | Streptomyces antibioticus | |
| 0.08 | - |
4-methoxyphenol | - |
Agaricus bisporus |  |
| 0.17 | - |
4-ethoxyphenol | - |
Agaricus bisporus | |
| 0.18 | - |
4-hydroxyphenyl acetic acid | - |
Neurospora crassa | |
| 0.21 | - |
L-Tyr | - |
Agaricus bisporus | |
| 0.32 | - |
D-Tyr | - |
Neurospora crassa | |
| 0.38 | - |
L-tyrosine methyl ester | - |
Agaricus bisporus | |
| 0.41 | - |
L-tyrosine | - |
Streptomyces glaucescens | |
| 0.44 | - |
4-hydroxyphenyl propionic acid | - |
Agaricus bisporus | |
| 0.48 | - |
4-hydroxyphenyl propionic acid | - |
Streptomyces glaucescens | |
| 0.51 | - |
tyramine | - |
Agaricus bisporus | |
| 0.59 | - |
L-Tyr | - |
Neurospora crassa | |
| 0.67 | - |
tyramine | - |
Neurospora crassa | |
| 0.7 | - |
phenol | - |
Agaricus bisporus | |
| 1.1 | - |
4-Hydroxybenzyl alcohol | - |
Agaricus bisporus | |
| 1.16 | - |
4-hydroxyphenyl acetic acid | - |
Streptomyces glaucescens | |
| 1.2 | - |
DL-2-methyltyrosine | - |
Agaricus bisporus | |
| 1.66 | - |
L-tyrosine methyl ester | - |
Streptomyces glaucescens | |
| 1.86 | - |
D-Tyr | - |
Agaricus bisporus | |
| 1.91 | - |
4-hydroxyphenyl acetic acid | - |
Agaricus bisporus | |
| 2.9 | - |
4-Fluorophenol | - |
Streptomyces antibioticus | |
| 5.4 | - |
3-methoxyphenol | - |
Agaricus bisporus | |
| 6.9 | - |
3-Fluorophenol | - |
Streptomyces antibioticus | |
| 10.1 | - |
3-Hydroxybenzyl alcohol | - |
Agaricus bisporus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Agaricus bisporus | - |
- |
- |
| Neurospora crassa | - |
- |
- |
| Streptomyces antibioticus | - |
- |
- |
| Streptomyces glaucescens | - |
- |
- |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Agaricus bisporus |
| additional information | - |
- |
Streptomyces glaucescens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3-fluorophenol + O2 | - |
Streptomyces antibioticus | ? | - |
? | |
| 3-hydroxybenzyl alcohol + O2 | - |
Agaricus bisporus | ? | - |
? | |
| 3-methoxyphenol + O2 | - |
Agaricus bisporus | ? | - |
? | |
| 4-ethoxyphenol + O2 | - |
Agaricus bisporus | ? | - |
? | |
| 4-fluorophenol + O2 | - |
Streptomyces antibioticus | ? | - |
? | |
| 4-hydroxybenzyl alcohol + O2 | - |
Agaricus bisporus | ? | - |
? | |
| 4-hydroxyphenyl acetic acid + O2 | - |
Neurospora crassa | ? | - |
? | |
| 4-hydroxyphenyl acetic acid + O2 | - |
Agaricus bisporus | ? | - |
? | |
| 4-hydroxyphenyl acetic acid + O2 | - |
Streptomyces glaucescens | ? | - |
? | |
| 4-hydroxyphenyl propionic acid + O2 | - |
Agaricus bisporus | ? | - |
? | |
| 4-hydroxyphenyl propionic acid + O2 | - |
Streptomyces glaucescens | ? | - |
? | |
| 4-methoxyphenol + O2 | - |
Agaricus bisporus | ? | - |
? | |
| D-tyrosine + L-dopa + O2 | - |
Neurospora crassa | D-dopa + dopaquinone + H2O | - |
? | |
| D-tyrosine + L-dopa + O2 | - |
Agaricus bisporus | D-dopa + dopaquinone + H2O | - |
? | |
| DL-2-methyltyrosine + O2 | - |
Agaricus bisporus | ? | - |
? | |
| L-tyrosine + L-dopa + O2 | - |
Neurospora crassa | L-dopa + dopaquinone + H2O | - |
? | |
| L-tyrosine + L-dopa + O2 | - |
Agaricus bisporus | L-dopa + dopaquinone + H2O | - |
? | |
| L-tyrosine + L-dopa + O2 | - |
Streptomyces glaucescens | L-dopa + dopaquinone + H2O | - |
? | |
| L-tyrosine methyl ester + O2 | - |
Agaricus bisporus | ? | - |
? | |
| L-tyrosine methyl ester + O2 | - |
Streptomyces glaucescens | ? | - |
? | |
| additional information | the enzyme catalyzes the hydroxylation of monophenols to o-diphenols, monophenolase activity EC 1.14.18.1, and the oxidation of the o-diphenols to o-quinones, diphenolase activity EC 1.10.3.1, cross-reaction analysis, overview | Neurospora crassa | ? | - |
? | |
| additional information | the enzyme catalyzes the hydroxylation of monophenols to o-diphenols, monophenolase activity EC 1.14.18.1, and the oxidation of the o-diphenols to o-quinones, diphenolase activity EC 1.10.3.1, cross-reaction analysis, overview | Agaricus bisporus | ? | - |
? | |
| additional information | the enzyme catalyzes the hydroxylation of monophenols to o-diphenols, monophenolase activity EC 1.14.18.1, and the oxidation of the o-diphenols to o-quinones, diphenolase activity EC 1.10.3.1, cross-reaction analysis, overview | Streptomyces glaucescens | ? | - |
? | |
| additional information | the enzyme catalyzes the hydroxylation of monophenols to o-diphenols, monophenolase activity EC 1.14.18.1, and the oxidation of the o-diphenols to o-quinones, diphenolase activity EC 1.10.3.1, cross-reaction analysis, overview | Streptomyces antibioticus | ? | - |
? | |
| phenol + O2 | - |
Agaricus bisporus | ? | - |
? | |
| tyramine + O2 | - |
Neurospora crassa | ? | - |
? | |
| tyramine + O2 | - |
Agaricus bisporus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| monophenolase | - |
Neurospora crassa |
| monophenolase | - |
Agaricus bisporus |
| monophenolase | - |
Streptomyces glaucescens |
| monophenolase | - |
Streptomyces antibioticus |
| More | cf. EC 1.10.3.1 | Neurospora crassa |
| More | cf. EC 1.10.3.1 | Agaricus bisporus |
| More | cf. EC 1.10.3.1 | Streptomyces glaucescens |
| More | cf. EC 1.10.3.1 | Streptomyces antibioticus |
| tyrosinase | - |
Neurospora crassa |
| tyrosinase | - |
Agaricus bisporus |
| tyrosinase | - |
Streptomyces glaucescens |
| tyrosinase | - |
Streptomyces antibioticus |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.6 | - |
DL-2-methyltyrosine | - |
Agaricus bisporus | |
| 3 | - |
3-Fluorophenol | - |
Streptomyces antibioticus | |
| 3.4 | - |
L-tyrosine methyl ester | - |
Agaricus bisporus | |
| 7.9 | - |
L-Tyr | - |
Agaricus bisporus | |
| 8 | - |
D-Tyr | - |
Agaricus bisporus | |
| 10.5 | - |
4-Fluorophenol | - |
Streptomyces antibioticus | |
| 12.1 | - |
3-Hydroxybenzyl alcohol | - |
Agaricus bisporus | |
| 12.7 | - |
phenol | - |
Agaricus bisporus | |
| 13.2 | - |
L-tyrosine | - |
Streptomyces glaucescens | |
| 20 | 50 | 4-Hydroxybenzyl alcohol | - |
Agaricus bisporus | |
| 25.9 | - |
tyramine | - |
Agaricus bisporus | |
| 44.3 | - |
4-hydroxyphenyl acetic acid | - |
Agaricus bisporus | |
| 46.8 | - |
3-methoxyphenol | - |
Agaricus bisporus | |
| 48.8 | - |
4-hydroxyphenyl acetic acid | - |
Streptomyces glaucescens | |
| 66.7 | - |
4-hydroxyphenyl propionic acid | - |
Agaricus bisporus | |
| 88.2 | - |
4-Hydroxybenzyl alcohol | - |
Agaricus bisporus | |
| 132 | - |
4-ethoxyphenol | - |
Agaricus bisporus | |
| 134 | - |
4-hydroxyphenyl propionic acid | - |
Streptomyces glaucescens | |
| 160 | - |
tyramine | - |
Neurospora crassa | |
| 160 | - |
D-Tyr | - |
Neurospora crassa | |
| 184 | - |
4-methoxyphenol | - |
Agaricus bisporus | |
| 235 | - |
L-tyrosine methyl ester | - |
Streptomyces glaucescens | |
| 250 | - |
4-hydroxyphenyl acetic acid | - |
Neurospora crassa | |
| 320 | - |
L-Tyr | - |
Neurospora crassa | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
