Literature summary for 1.14.17.4 extracted from

Datta, R.; Kumar, D.; Sultana, A.; Hazra, S.; Bhattacharyya, D.; Chattopadhyay, S.
Glutathione regulates 1-aminocyclopropane-1-carboxylate synthase transcription via WRKY33 and 1-aminocyclopropane-1-carboxylate oxidase by modulating messenger RNA stability to induce ethylene synthesis during stress (2015), Plant Physiol., 169, 2963-2981 .

Search for more literature for 1.14.17.4

Cloned(Commentary)

Cloned (Comment)	Organism
gene aco1, quantitative RT-PCR expression analysis, analysis of promoter activity of proACO1 in response to GSH and ethephon feeding, expression profiles of ACO1, overview. The activity of ACO1 promoter is unaffected by GSH feeding, but its activity increases significantly on Eth feeding. GSH enhances the mRNA stability of ACO1	Arabidopsis thaliana

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
protoplast	-	Arabidopsis thaliana	-	-

Organism

Organism	UniProt	Comment	Textmining
Arabidopsis thaliana	Q42560	-	-
Arabidopsis thaliana Col-0	Q42560	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
additional information	the ACO1 protein is a subject for S-glutathionylation, homology modeling and docking analysis reveals that ACO1 is S-glutathionylated on residue CYS63	Arabidopsis thaliana

Source Tissue

Source Tissue	Comment	Organism	Textmining
leaf	-	Arabidopsis thaliana	-

Subunits

Subunits	Comment	Organism
More	ACO1 structure homology modeling, comparative protein structure modeling, and three-dimensional structure of AtACO1, overview	Arabidopsis thaliana

Synonyms

Synonyms	Comment	Organism
1-aminocyclopropane-1-carboxylate oxidase	-	Arabidopsis thaliana
Aco1	-	Arabidopsis thaliana
AtACO1	-	Arabidopsis thaliana

Expression

Organism	Comment	Expression
Arabidopsis thaliana	transgenic Arabidopsis thaliana phytoalexin deficient2-1 (pad2-1) mutant.plants with depleted GSH content exhibit remarkable downregulation of ACS2, ACS6, and ACO1 at transcript as well as protein levels. The ACO1 gene is remarkably downregulated in pad2-1, a GSH-depleted phytoalexin deficient 2-1 mutant	down
Arabidopsis thaliana	ascorbate feeding fails to increase ACO1 transcript and protein abundance in the pad2-1 mutant	additional information
Arabidopsis thaliana	transgenic Arabidopsis thaliana plants with enhanced GSH content exhibit remarkable upregulation of ACS2, ACS6, and ACO1 at transcript as well as protein levels. The ACO1 gene is remarkably upregulated in AtECS1 (plants with enhanced GSH content). Stronger induction of ACS2, ACS6, andACO1 genes is observed in AtECS1 during infection with Bacillus cinerea as well as salt stress, while a weaker induction is observed in pad2-1 mutant	up

General Information

General Information	Comment	Organism
metabolism	glutathione (GSH) plays a fundamental role in plant defense-signaling network. GSH can bind residue CYS63 of AtACO1 protein. Transgenic Arabidopsis thaliana plants with enhanced GSH content exhibit remarkable upregulation of ACS2, ACS6, and ACO1 at transcript as well as protein levels, while they are downregulated in the GSH depleted phytoalexin deficient2-1 (pad2-1) mutant. GSH induced ACS2 and ACS6 transcription in a WRKY33-dependent manner, while ACO1 transcription remained unaffected although the mRNA stability for ACO1 is increased by GSH, the ACO1 protein is a subject for S-glutathionylation, while S-glutathionylation of ACS2 and ACS6 proteins is not detected. Transcriptional regulation of gene ACO1, overview. ACO1 expressin is not significantly altered in a wrky33 mutant. GSH-mediated ACO1 regulation is not due to ascorbate limitation. GSH plays a role in maintaining the mRNA stability for ACO1	Arabidopsis thaliana
additional information	homology modeling and docking analysis reveals that ACO1 is S-glutathionylated on residue CYS63	Arabidopsis thaliana
physiological function	transcriptional regulation of gene ACO1, overview	Arabidopsis thaliana

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Release 2023.1 (January 2023)