Cloned (Comment) | Organism |
---|---|
expressed in Sf9 cell | Xenopus laevis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(R)-5-acetamido-4-oxo-6-phenyl-2-hexenoic acid | reversible and irreversible inhibition | Xenopus laevis | |
(S)-5-acetamido-4-oxo-6-phenyl-2-hexenoic acid | reversible and irreversible inhibition | Xenopus laevis | |
(S)-5-acetamido-7-methylthio-4-oxo-2-heptenoic acid | reversible and irreversible inhibition | Xenopus laevis | |
N-acetyl-D-Leu-OCH2COOH | competitive inhibitor | Xenopus laevis | |
N-acetyl-D-Phe-Gly | - |
Xenopus laevis | |
N-acetyl-L-Leu-OCH2COOH | competitive inhibitor | Xenopus laevis | |
N-acetyl-L-Phe-OCH2COOH | competitive inhibitor | Xenopus laevis | |
O-acetyl-D-mandelyl-Gly | - |
Xenopus laevis |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0079 | - |
N-acetyl-L-Phe-Gly | pH not specified in the publication, temperature not specified in the publication | Xenopus laevis | |
0.17 | - |
O-acetyl-L-mandelyl-Gly | pH not specified in the publication, temperature not specified in the publication | Xenopus laevis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Xenopus laevis | - |
- |
- |
Purification (Comment) | Organism |
---|---|
cation-exchange chromatography, anion-exchange chromatography, gel filtration | Xenopus laevis |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
skin | - |
Xenopus laevis | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-acetyl-L-Phe-Gly + ascorbate + O2 | - |
Xenopus laevis | N-acetyl-L-Phe-2-hydroxyglycine + dehydroascorbate + H2O | - |
? | |
O-acetyl-L-mandelyl-Gly + ascorbate + O2 | - |
Xenopus laevis | O-acetyl-L-mandelyl-2-hydroxyglycine + dehydroascorbate + H2O | - |
? | |
peptidylglycine + ascorbate + O2 | - |
Xenopus laevis | peptidyl (S)-2-hydroxyglycine + dehydroascorbate + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
peptidylglycine alpha-monooxygenase | - |
Xenopus laevis |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0452 | - |
N-acetyl-L-Phe-OCH2COOH | pH not specified in the publication, temperature not specified in the publication | Xenopus laevis | |
0.054 | - |
(S)-5-acetamido-4-oxo-6-phenyl-2-hexenoic acid | pH 6.5, 37°C | Xenopus laevis | |
0.057 | - |
(S)-5-acetamido-7-methylthio-4-oxo-2-heptenoic acid | pH 6.5, 37°C | Xenopus laevis | |
0.0598 | - |
N-acetyl-L-Leu-OCH2COOH | pH not specified in the publication, temperature not specified in the publication | Xenopus laevis | |
0.06 | - |
(R)-5-acetamido-4-oxo-6-phenyl-2-hexenoic acid | pH 6.5, 37°C | Xenopus laevis | |
1.3 | - |
N-acetyl-D-Phe-Gly | pH not specified in the publication, temperature not specified in the publication | Xenopus laevis | |
2.1 | - |
N-acetyl-D-Leu-OCH2COOH | pH not specified in the publication, temperature not specified in the publication | Xenopus laevis | |
8.1 | - |
O-acetyl-D-mandelyl-Gly | pH not specified in the publication, temperature not specified in the publication | Xenopus laevis |