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Literature summary for 1.14.17.1 extracted from

  • Xu, Q.; Song, Y.; Liu, R.; Chen, Y.; Zhang, Y.; Li, Y.; Zhao, W.; Chang, G.; Chen, G.
    The dopamine beta-hydroxylase gene in Chinese goose (Anas cygnoides) cloning, characterization, and expression during the reproductive cycle (2016), BMC Genet., 17, 48 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.14.17.1

Cloned(Commentary)

Cloned (Comment) Organism
gene gDBH, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, real-time quantitative PCR enzyme expression analysis Anser cygnoides domesticus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
dopamine + ascorbate + O2 Anser cygnoides domesticus
-
 noradrenaline + dehydroascorbate + H2O
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 ?

Organism

Organism UniProt Comment Textmining
Anser cygnoides domesticus A0A140GN70
-
-

Source Tissue

Source Tissue Comment Organism Textmining
endocrine gland
-
 Anser cygnoides domesticus
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hypothalamus
-
 Anser cygnoides domesticus
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additional information gDBH expression is found between the hypothalamus-pituitary and oviduct during the ovulation phase and the broody phase, real-time quantitative PCR enzyme expression analysis. The enzyme expression is higher in animals with higher egg production than in those with low egg production. Analysis of temporal expression patterns of gDBH expression in the hypothalamus, pituitary, ovary, and oviduct tissues during different stages of the goose reproductive cycle, specifically the pre-laying stage, ovulation, oviposition, and the broody phase reveals that the expression is lowest in all tissues during the oviposition phase. It is high in the hypothalamus, ovary, and pituitary in the pre-laying period. High expression of DBH is also found in the cerebrum and cerebellum due to the involvement of norepinephrine and epinephrine in neuroendocrine processes Anser cygnoides domesticus
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oviduct
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 Anser cygnoides domesticus
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pituitary gland
-
 Anser cygnoides domesticus
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reproductive tissue
-
 Anser cygnoides domesticus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dopamine + ascorbate + O2
-
 Anser cygnoides domesticus noradrenaline + dehydroascorbate + H2O
-
 ?

Synonyms

Synonyms Comment Organism
DBH
-
 Anser cygnoides domesticus
dopamine beta-hydroxylase
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 Anser cygnoides domesticus
gDBH
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 Anser cygnoides domesticus

Cofactor

Cofactor Comment Organism Structure
ascorbate
-
 Anser cygnoides domesticus

General Information

General Information Comment Organism
physiological function dopamine beta-hydroxylase is a critical enzyme in the biosynthesis of catecholamines with a role in neuroendocrine regulation and in avian reproduction. Dopamine beta-hydroxylase catalyzes the conversion of dopamine to norepinephrine in the biosynthesis of catecholamines. The activity of DBH influences the levels of dopamine and the biosynthesis of norepinephrine and epinephrine. The enzyme is important in the nervous system Anser cygnoides domesticus