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Literature summary for 1.14.17.1 extracted from

  • Mustapic, M.; Pivac, N.; Kozaric-Kovacic, D.; Dezeljin, M.; Cubells, J.F.; Mueck-Seler, D.
    Dopamine beta-hydroxylase (DBH) activity and -1021C/T polymorphism of DBH gene in combat-related post-traumatic stress disorder (2007), Am. J. Med. Genet. B Neuropsychiatr. Genet., 144B, 1087-1089.
    View publication on PubMed

Application

Application Comment Organism
diagnostics genotype-controlled measurement of plasma DBH activity might be used as a potential biological marker of the response to trauma Homo sapiens

Protein Variants

Protein Variants Comment Organism
C1021T naturally occuring gene polymorphism, determination of the frequency in combat veterans with or without chronic posttraumatic stress disorder, overview Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens a significantly lower plasma DBH activity is found in combat veterans with posttraumatic stress disorder carrying the CC genotype as compared to veterans without posttraumatic stress disorder carrying the corresponding genotype, dependent on the genotype the regulation of DBH expression is different in response to trauma, overview ?
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?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
plasma enzyme activity in plasma from combat veterans with or without chronic posttraumatic stress disorder, non-normal distribution, overview Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
enzyme activity in plasma from combat veterans with or without chronic posttraumatic stress disorder, overview Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information a significantly lower plasma DBH activity is found in combat veterans with posttraumatic stress disorder carrying the CC genotype as compared to veterans without posttraumatic stress disorder carrying the corresponding genotype, dependent on the genotype the regulation of DBH expression is different in response to trauma, overview Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
DBH
-
Homo sapiens
dopamine beta-hydroxylase
-
Homo sapiens