KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
3.8 | - |
2-aminoindane | 37°C, 0.2 M acetate buffe, pI 6, with 30 mM NEM, 1 mM K4Fe(CN)6, 5 mM CuSO4 | Bos taurus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partially, from adrenal medulla after crude extract PEG 6000 precipitation and DEAE-Sepharose chromatography | Bos taurus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-aminoindane + ascorbate + O2 | Stereochemistry is in contrast to the stereochemical course of pro-R hydroxylation of the DBH/phenethylamine reaction. Studies with stereospecifically deuterium labelled substrate show that the production of (1S)-aminoindanol ir the result of sterospecific pro-S hydrogen abstraction followed by the oxygen binding with overall retention of configuration | Bos taurus | trans-(1S,2S)-2-amino-1-indanol + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
DBH | - |
Bos taurus |
dopamine beta-hydroxylase | - |
Bos taurus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ascorbate | - |
Bos taurus |