Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli BL21(DE3) as His-tag fusion protein | Rattus norvegicus |
Protein Variants | Comment | Organism |
---|---|---|
S19E | mimics phosphorylation at S19 | Rattus norvegicus |
S19E/S40E | mimics phosphorylation at S19S40 | Rattus norvegicus |
S31E | mimics phosphorylation at S31 | Rattus norvegicus |
S40E | mimics phosphorylation at S40 | Rattus norvegicus |
S8E | mimics phosphorylation at S8 | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | phosphorylation occurs at S8, S19, S31 and S40. Neither cAMP-dependent protein kinase nor extracellular signal-regulated kinase 2 activity for phosphorylation of tyrosine hydroxylase is affected by pre-existing phosphorylations. Phosphorylation of S40 by cAMP-dependent protein kinase is inhibited by bound dopamine | Rattus norvegicus |
Purification (Comment) | Organism |
---|---|
Ni-affinity chromatography | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cell culture | - |
Rattus norvegicus | - |
Synonyms | Comment | Organism |
---|---|---|
TyrH | - |
Rattus norvegicus |
tyrosine hydroxylase | - |
Rattus norvegicus |