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Literature summary for 1.14.16.2 extracted from
- Reduction and oxidation of the active site iron in tyrosine hydroxylase: kinetics and specificity (2006), Biochemistry, 45, 2372-2379.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli BL21(DE3) | Homo sapiens |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| E332A | the mutant has 10fold higher Km for 6-methyltetrahydropterin, but reduction of the enzyme by 6-methyltetrahydropterin is similar to the wild type | Homo sapiens |
| S40E | the mutant mimics a phosphorylation of S40. The kinetics of reduction and oxidation of the enzyme are similar to the wild type | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| Hi-TRAP heparin column | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cell culture | - |
Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| TyrH | - |
Homo sapiens |
| tyrosine hydroxylase | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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