Activating Compound | Comment | Organism | Structure |
---|---|---|---|
L-phenylalanine | - |
Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
E76A | the mutation is associated with phenylketonuria | Homo sapiens |
G46S | the mutation is associated with phenylketonuria | Homo sapiens |
I65S | the mutation is associated with phenylketonuria | Homo sapiens |
T63P | the mutation is associated with phenylketonuria | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
26300 | - |
catalytic domain, calculated from amino acid sequence | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-phenylalanine + tetrahydrobiopterin + O2 | Homo sapiens | - |
L-tyrosine + 4a-hydroxytetrahydrobiopterin | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P00439 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-phenylalanine + tetrahydrobiopterin + O2 | - |
Homo sapiens | L-tyrosine + 4a-hydroxytetrahydrobiopterin | - |
? |
Subunits | Comment | Organism |
---|---|---|
homodimer | 2 * 13500, catalytic domain, calculated from amino acid sequence | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
PAH | - |
Homo sapiens |
phenylalanine hydroxylase | - |
Homo sapiens |