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Literature summary for 1.14.16.1 extracted from

  • Boonyapiwat, B.; Panagopoulos, P.; Jones, H.; Mitchell, S.C.; Forbes, B.; Steventon, G.B.
    Phenylalanine 4-monooxygenase and the S-oxidation of S-carboxymethyl-L-cysteine in HepG2 cells (2005), Drug Metabol. Drug Interact., 21, 1-18.
    View publication on PubMed
Search for more literature for 1.14.16.1

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
7.14
-
 L-phenylalanine
-
 Homo sapiens
25.24
-
 S-carboxymethyl-L-cysteine
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Homo sapiens 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-phenylalanine + tetrahydrobiopterin + O2 Homo sapiens modelling of cellular regulation L-tyrosine + 4a-hydroxy-tetrahydrobiopterin
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Hep-G2 cell
-
 Homo sapiens
-
hepatocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-phenylalanine + tetrahydrobiopterin + O2
-
 Homo sapiens L-tyrosine + 4a-hydroxy-tetrahydrobiopterin
-
 ?
L-phenylalanine + tetrahydrobiopterin + O2 modelling of cellular regulation Homo sapiens L-tyrosine + 4a-hydroxy-tetrahydrobiopterin
-
 ?
S-carboxymethyl-L-cysteine + tetrahydrobiopterin + O2 conversion to the (S)-sulfoxide Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
PAH
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
tetrahydrobiopterin
-
 Homo sapiens