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Literature summary for 1.14.15.6 extracted from

  • Nakamoto, M.; Fukasawa, M.; Orii, S.; Shimamori, K.; Maeda, T.; Suzuki, A.; Matsuda, M.; Kobayashi, T.; Nagahama, Y.; Shibata, N.
    Cloning and expression of medaka cholesterol side chain cleavage cytochrome P450 during gonadal development (2010), Dev. Growth Differ., 52, 385-395.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
DNA and amino acid sequence determination and analysis, expression analysis and sequence comparisons Oryzias latipes

Organism

Organism UniProt Comment Textmining
Oryzias latipes
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Source Tissue

Source Tissue Comment Organism Textmining
gonad female and male, expression pattern of P450scc mRNA during gonadal development using in situ hybridization, overview. In male gonads, expression of P450scc occurs in the interstitial somatic cells 15 days after hatching following the formation of the seminiferous tubule precursor, and is maintained in the interstitial somatic cells throughout testicular development. In the female gonad, expression of P450scc initially occurs in interstitial somatic cells 5 days after hatching and subsequently occurs continuously in the interstitial somatic cells of the developing ovary Oryzias latipes
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ovary strong 450scc mRNA signal in the vitellogenic ovarian follicles of adult ovaries, P450scc is not detected in postvitellogenic follicles Oryzias latipes
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testis developing, in interstitial region between testicular tubules, expression pattern of medaka P450scc during testicular development, overview Oryzias latipes
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Synonyms

Synonyms Comment Organism
cholesterol side chain cleavage cytochrome P450
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Oryzias latipes
Cyp11a
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Oryzias latipes
P450scc
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Oryzias latipes

General Information

General Information Comment Organism
metabolism Cyp11a is responsible for the first step in steroidogenesis, catalyzing the conversion of cholesterol to prognenolone Oryzias latipes