Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.14.15.4 extracted from

  • Neunzig, J.; Khatri, Y.; Bernhardt, R.
    The impact of the clinical CYP11B2 mutation V386A strongly depends on the enzymes genetic background (2017), Endocr. J., 64, 457-461 .
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Homo sapiens

Protein Variants

Protein Variants Comment Organism
V386A the combination of the V386A mutation with the variant CYP11B2 173Arg only slightly reduces the 18-hydroxylase and 18-oxidase activity, whereas the V386A mutation with the CYP11B2 173Lys variant almost abolishes the 18-hydroxylation and 18-oxidation. In both cases the 11-hydroxylase activity is not affected Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P19099
-
-

Synonyms

Synonyms Comment Organism
CYP11B2
-
Homo sapiens
cytochrome P450 11B2
-
Homo sapiens