Activating Compound | Comment | Organism | Structure |
---|---|---|---|
malate | supports 1alpha-hydroxylation as electron donor | Gallus gallus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | - |
Gallus gallus | |
ethylene glycol-bis(beta-aminoethyl ether)-N,N,N',N'-tetraacetic acid | - |
Gallus gallus | |
phosphate | - |
Gallus gallus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Gallus gallus | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Gallus gallus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Gallus gallus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.0000031 | - |
- |
Gallus gallus |
0.0000048 | - |
with malate as electron source | Gallus gallus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
calcidiol + NADPH + O2 | highly specific for calcidiol, calcidiol is identical with 25-hydroxycholecalciferol | Gallus gallus | calcitriol + NADP+ + H2O | calcitriol is identical with 1,25-dihydroxycholecalciferol | ? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Gallus gallus |